Food Business News - May 26, 2020 - 44

Studies link a saturated fat to reduced risk of diseases

S

eraphina Therapeutics, Inc. on May 18
announced plans to commercialize a
saturated fat called pentadecanoic acid,
also known as C15:0. The same day Seraphina Therapeutics researchers associated C15:0
with lower risk of inflammation, cardiovascular disease and non-alcoholic fatty
liver disease in an article online in Scientific
Reports. The researchers proposed C15:0 as a
potential essential fatty acid.
Seraphina Therapeutics plans to launch
a C15:0 dietary supplement in the fall and a
C15:0 ingredient to fortify foods early next
year. The company has received Series A
funding of $5.5 million led by Domain Associates, a venture capital firm.
"We surprisingly found a trace saturated fat in butter that is repeatedly demonstrating evidence of broad health effects
across a variety of studies," said Stephanie
Venn-Watson, DVM, co-founder and chief

executive officer for Seraphina Therapeutics.
An odd-chained saturated fatty acid,
C15:0 is found in butter and some fish and
plants. Dr. Venn-Watson said saturated fat is
divided into two categories: even-chained
and odd-chained. Most food items primarily
have even-chained saturated fatty acids,
which are associated with a greater risk of
cardiovascular disease and diabetes, she said.
"That's why we've seen so much literature around saturated fats being bad," Dr.
Venn-Watson said.
In contrast, C15:0 makes up 1% of the
fatty acids in whole fat milk.
Researchers at Seraphina Therapeutics suggest people eating less butter and
whole fat milk over the past 40 years has led
to a decrease in C15:0 intake. The amount
of C15:0 in the bloodstream is a biomarker
for how much dairy someone has eaten,
Dr. Venn-Watson said, adding research also

C15:0 comes in
powder form
and has no taste
or off odor.

SERAPHINA THERAPEUTICS

has shown that people with high levels of
C15:0 are linked to lower risks of numerous
diseases.
Both omega-3 fatty acids and C15:0 fatty acids provide health benefits but in different ways.
"If we talk about omega-3 vs C15, they
are kind of like the yin and yang of fatty
acids," Dr. Venn-Watson said.
Omega-3 fatty acids enter cell membranes and make them nice and flexible, she

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Food Business News - May 26, 2020

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Food Business News - May 26, 2020 - 1
Food Business News - May 26, 2020 - 1
Food Business News - May 26, 2020 - 2
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